public static class LayoutFrameworkExtender 

//Open a layout project item in a new view.
//A layout project item may exist but it may not be open in a view. 

//Reference a layout project item by name
LayoutProjectItem someLytItem = Project.Current.GetItems<LayoutProjectItem>().FirstOrDefault(item => item.Name.Equals("MyLayout"));

//Get the layout associated with the layout project item
Layout layout = await QueuedTask.Run(() => someLytItem.GetLayout());  //Worker thread

//Create the new pane
ILayoutPane iNewLayoutPane = await ProApp.Panes.CreateLayoutPaneAsync(layout); //GUI thread

//This sample checks to see if a layout project item already has an open application pane.  
//If it does, it checks if it is the active layout view, if not, it creates, activates and opens a new pane.

//Reference a layoutitem in a project by name
LayoutProjectItem layoutItem = Project.Current.GetItems<LayoutProjectItem>().FirstOrDefault(item => item.Name.Equals("Layout View"));

//Get the layout associated with the layoutitem
Layout lyt = await QueuedTask.Run(() => layoutItem.GetLayout());
      
//Iterate through each pane in the application and check to see if the layout is already open and if so, activate it
foreach (var pane in ProApp.Panes)
{
  var layoutPane = pane as ILayoutPane;
  if (layoutPane == null)  //if not a layout pane, continue to the next pane
    continue;
  if (layoutPane.LayoutView.Layout == lyt)  //if the layout pane does match the layout, activate it.
  {
    (layoutPane as Pane).Activate();
    layoutPane.Caption = "This is a test";
    System.Windows.MessageBox.Show(layoutPane.Caption);
    return;
  }
}
//Otherwise, create, open, and activate the layout if not already open
ILayoutPane newPane = await ProApp.Panes.CreateLayoutPaneAsync(lyt);

//Zoom to the full extent of the layout
await QueuedTask.Run(() => newPane.LayoutView.ZoomTo100Percent());

//Find and close all layout panes associated with a specific layout.

LayoutProjectItem findLytItem = Project.Current.GetItems<LayoutProjectItem>().FirstOrDefault(item => item.Name.Equals("Layout"));
Layout findLyt = await QueuedTask.Run(() => findLytItem.GetLayout());  //Perform on the worker thread

var panes = ProApp.Panes.FindLayoutPanes(findLyt);
foreach (Pane pane in panes)
{
  ProApp.Panes.CloseLayoutPanes(findLyt.URI);  //Close the pane
}